PREVALENCE OF INTEGRATED HBV DNA AMONG BLOOD DONORS IN EGYPT

Authors

  • M. A. RASHED Genetics Dep., Faculty of Agriculture, Ain Shams University
  • M. A. SWELIM Faculty of Science, Bot. Dep., Benha University
  • S. H. ABDEL-AZIZ Faculty of Science, Bot. Dep., Benha University
  • I. M. ELKALAMAWY Research & Development Dep., Egyptian Company for Blood Transfusion Services. (Egyblood/VACSERA)

Abstract

This study presented important data about the gap between serology screening (surface antigen) and nucleic acid testing (NAT) testing of blood donors. Effectiveness of NAT for blood donors screening is a debating area in blood transfusion. This study highlight on the riskiness of transfuse blood contain integrated HBV DNA owing to the carcinogenic effect of integrated HBV in human liver. Wide-national study is required to ensure blood transfusion safety and effectiveness by using traditional (surface antigen, core antigen as a serological test) confirmed by NAT testing to screen blood donors and introduce new techniques for the detection of viral integrated with the human genome.

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Published

2017-01-19

Issue

Vol. 45 No. 2 (2016)

Section

Articles