EFFECT OF VARIATION IN THE ADRENERGIC RECEPTOR BETA 3 (ADRβ3) GENE ON WOOL TRAITS IN BARKI SHEEP
Abstract
The adrenergic receptor β3 (ADRβ3) gene encodes for ADRβ3 which is mainly expressed in white and brown adipose tissues of mammals and plays a crucial role in energy homeostasis that affect the various tissues and organs including wool follicle that controls wool growth and traits. The objective of this study was to test the association between the variation in ADRβ3 gene and some wool traits (greasy wool per unit area, clean wool per unit area, clean wool yield, mean fiber diameter, medullation percentage, mean staple crimp, mean staple length, mean staple strength, prickle factor value, elongation percentage and point of break in 57 males of Barki lambs using the polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP) tool. General linear mixed effect models were used to test the effect of ADRβ3 genotype or the presence/ absence of ADRβ3 alleles in animal genotype on the studied wool traits. The genotype of ADRβ3 had significant effect (P ˂ 0.05) on clean wool yield, mean staple strength and prickle factor value. The presence of allele C and the absence of allele A in animal genotype were significantly associated with increased clean wool yield, increased mean staple strength and decreased prickle factor value. The results presented here give valuable information to select for allele C and against allele A to improve some of the most important wool traits in Barki sheep.References
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